Psychedelic-Adjacent Supplements Come to Market

Published 23 November 2022

2 min read

Signalling Americans’ growing openness to mind-altering substances, this month Coloradans voted to legalise certain psychedelics, following

  • Psychedelic Complements: US company Revitalist, which operates ketamine clinics, has created Vital+, a supplement line designed to complement psychedelic therapy, according to a press release. The brand site, however, avoids mentioning psychedelics, focusing on the products’ benefits for energy, memory, mood and immune response. The two supplements are sold at Revitalist’s centres and online. Morning pill Revive+ is formulated with B vitamins, magnesium, adaptogens and functional mushrooms, while evening pill Restore+ includes melatonin, ashwagandha and valerian.

  • Mushrooms Made Milder: Canadian life sciences start-up Psyched Wellness has launched flagship product Calm, a detoxified liquid extraction of Amanita muscaria – the white-speckled reddish mushroom known for its hallucinogenic properties. Promoting its benefits for sleep, the company says Calm is the only Amanita muscaria supplement legally approved for sale in the US. For details on the broader embrace of fungi, Stylus members can access Ingredient Index 03: Mushrooms and Beauty’s Mushroom Boom.

  • Commercialising Empathogenics: Several companies are leveraging South African mood-boosting botanical Kanna (central to Indigenous Khoisan medicinal and spiritual culture), which has been touted as “nature’s MDMA.” Kanna is an empathogenic, described by New York-based Ka! Empathogenics as “[helping] you feel a fuller sense of aliveness and a deeper connection to yourself and others” – a psychoactive (affecting the mind and mental processes), rather than a psychedelic (altering perception). Ka!’s chews are also formulated with acmella, which imparts a tingle when consuming the product. California-based Hearthstone Collective sells two Kanna-based products, revitalising Play and restorative Relax.


For more on the burgeoning consumer and corporate interest in psychedelics, Stylus members can access Solace Seekers and Retail & Media’s New Wellness Narratives.

  • Psychedelic Complements: US company Revitalist, which operates ketamine clinics, has created Vital+, a supplement line designed to complement psychedelic therapy, according to a press release. The brand site, however, avoids mentioning psychedelics, focusing on the products’ benefits for energy, memory, mood and immune response. The two supplements are sold at Revitalist’s centres and online. Morning pill Revive+ is formulated with B vitamins, magnesium, adaptogens and functional mushrooms, while evening pill Restore+ includes melatonin, ashwagandha and valerian.

  • Mushrooms Made Milder: Canadian life sciences start-up Psyched Wellness has launched flagship product Calm, a detoxified liquid extraction of Amanita muscaria – the white-speckled reddish mushroom known for its hallucinogenic properties. Promoting its benefits for sleep, the company says Calm is the only Amanita muscaria supplement legally approved for sale in the US. For details on the broader embrace of fungi, Stylus members can access Ingredient Index 03: Mushrooms and Beauty’s Mushroom Boom.

  • Commercialising Empathogenics: Several companies are leveraging South African mood-boosting botanical Kanna (central to Indigenous Khoisan medicinal and spiritual culture), which has been touted as “nature’s MDMA.” Kanna is an empathogenic, described by New York-based Ka! Empathogenics as “[helping] you feel a fuller sense of aliveness and a deeper connection to yourself and others” – a psychoactive (affecting the mind and mental processes), rather than a psychedelic (altering perception). Ka!’s chews are also formulated with acmella, which imparts a tingle when consuming the product. California-based Hearthstone Collective sells two Kanna-based products, revitalising Play and restorative Relax.


For more on the burgeoning consumer and corporate interest in psychedelics, Stylus members can access Solace Seekers and Retail & Media’s New Wellness Narratives.

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This article is an example of Stylus' expert research into how Food + Beverage trends are evolving. Get in touch so someone from the Stylus team can explain how your business can harness the power of trends and insights like these – and more.

Want to know more?

This article is an example of Stylus' expert research into how Food + Beverage trends are evolving. Get in touch so someone from the Stylus team can explain how your business can harness the power of trends and insights like these – and more.